Endocrine Abstracts

Introduction: The use of iodinated contrast media (ICM) can lead to thyrotoxicosis, especially in patients with risk factors, such as Graves’ disease, multinodular goiter, older age, and iodine deficiency. Although hyperthyroidism may have clinically relevant effects, whether high-risk patients should receive prophylactic treatment before they are administered ICM is still debated.Aim of the study: We aimed to demonstrate the safety and efficacy of ...

A 52-year man came to Emergency Department with Atrial Fibrillation with rapid ventricular response due to amiodarone induced thyrotoxicosis (AIT). The patient was found tachi-arrhythmic (153 beats per minute), tachypnoic (27 breaths per minute) and with intense hyperidrosis. His first blood test documented thyroid stimulating hormone (TSH) <0.01 mUI/l, free triiodothyronine (fT3) 20.0 pmol/l and free thyroxine (fT4) over 100 pmol/l. Thyroid ultrasonography revealed an enl...

Introduction: Thyroid eye disease (TED) is an immune-mediated disorder of the eye. Intravenous glucocorticoid (GC) is the first-line treatment for active moderate to severe TED patients. However, the rate of response is between 50 and 80%. Reliable and easily accessible markers of responsiveness to GC therapy are still lacking.Aim of the study: We aimed to explore the possible role of miR-146a and miR-21 as a predictor of responsiveness to GC treatment i...